Dog suffering with allergies? Here’s what’s really going on.

Exploring the best supplements for dogs with allergies: a practical, research focussed guide.

Max Hancock | 27th October 2025

Finding the best supplements for dogs with allergies can be a challenging search, because “allergy” can look like a dozen (or even a thousand, sometimes) different things. This article breaks down the latest research into plain English, and offers practical takeaways for how you can help your dog.

Overview & Key Takeaways

Allergies in dogs can show up as itchy skin, ear irritation, tummy upsets, or runny eyes - whilst allergy ‘triggers’ range from food proteins to pollen, dust mites, or even cleaning products. True allergies involve an over-reactive immune system, while mild sensitivities can mimic full blown allergies. Here we explore key differences, and how certain ingredients in your dog’s diet such as probiotics, omega-3s, and antioxidants, may support normal immune balance and skin comfort. We’ll also cover when to seek veterinary advice, and how to pick supplements that make practical sense without masking the real issue.

Reading time:

5 minutes

What you‘ll find in this article:

  1. Allergies in dogs: what’s actually happening
  2. How to distinguish between allergies and sensitivities
  3. Gut and immune balance explained
  4. Probiotics, omega-3s and antioxidants that can help
  5. When your dog’s symptoms require further investigation

What ‘allergy’ really means 

A true allergy is an immune overreaction to something typically harmless, often referred to as a ‘trigger’ - things like certain food proteins, pollen, or dust. When the body encounters these triggers, the immune system produces antibodies (known as IgE antibodies), that bind to immune cells. The immune cells release histamine, which causes itching, redness, swelling and irritation - this is what owners see as scratching, paw licking, or ear shaking. 

Sensitivities on the other hand, whilst they look similar in their presentation, do not involve this same IgE-histamine pathway. They tend to cause mild gut or skin upset, rather than a full blown immune response.

Research shows that up to 20% of itchy dogs seen by vets have an allergic cause, so it’s surprisingly common in our dog population. Atopic dermatitis, a term used for different types of skin inflammation, typically characterised by itchiness, redness and a rash, is the most common vet presentation (1).

Common signs of allergies in dogs

Unsurprisingly, the most common ‘signs’ are scratching/itching, paw licking, red patches, chronic runny eyes and repeated ear infections. Some dogs get soft or loose stools, or frequent bloating and tummy noises. The pattern of these allergic signs - whether they’re seasonal or year-round - can give your vet clues as to what might be the trigger. The BSAVA Dermatology Manual suggests that allergic skin conditions often appear between 1-3 years of age, and may worsen seasonally (1), whether the trigger is seasonal or not.

How the gut and immune system are connected

A large proportion of immune cells are associated with the gut (5, 6, 7, 8), which is why the digestive system gets so much attention in animal health. When the gut microbiome is out of balance, the immune system can overreact to otherwise harmless triggers. There is research evidence to show that probiotics can modulate immune markers (i.e. keep the immune system balanced), and support skin barrier health in dogs with allergies conditions (2, 5). 

Supportive nutrients that can help

There is growing evidence that certain probiotics may help maintain a balanced gut microbiome and support normal immune responses. Omega-3 fatty acids have also been reported to reduce itch scores, and improve coat condition in dogs with allergic skin disease (3, 7), alongside things such as Zinc and Biotin.

Antioxidants, such as Vitamin C and Vitamin E, selenium and polyphenols, can help to reduce oxidative stress during flare-ups (i.e. deal with inflammation more smoothly). In one particular study, antioxidant supplementation was associated with improved measured immune responses to vaccination (8): in other words, whilst it didn't make the vaccine 'better', the dogs showed slightly stronger immune reactions when they were vaccinated, after supplementation.

Choosing the right supplement

Supplement choice can be overwhelming, and whilst supplements themselves do not replace professional diagnosis, they can help to maintain comfort. Evaluate supplement labels for transparent and clear declared active ingredients (4), minimal artificial flavourings or useless additives, and clear traceability. Introduce any new supplements gradually, one at a time, and keep a record of changes in your dog’s condition and wellbeing. 

When to see your vet

Veterinary dermatologists recognise that only diagnostic testing confirms allergy triggers (2), but constant ear scratching, head shaking, sores or red patches, persistent tummy upsets or loose poops may indicate your dog requires attention from your vet. They can run skin tests, or elimination trials, to identify triggers.

Pawburst Roundup

Allergies in dogs aren’t one-size-fits-all, but understanding what’s going on inside can help it feel like less of a mystery. Look for clearly labelled, traceable active ingredients with measured quantities, and choose quality nutrients that are backed by clinical research. Keep your vet in the loop if you need extra assistance.

Disclaimer

This article is for general information only and does not replace veterinary advice. Supplements and nutritional products are not licensed veterinary medicines. Always speak to your vet before making changes to your dog’s diet, supplements, or care routine.

References

  1. Outerbridge CA. Current knowledge on canine atopic dermatitis. Vet Sci. 2021;8(7):122.
    Open-access review on CAD presentation, age of onset, seasonality patterns. Use this where you discuss “common” allergic presentations and seasonality. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC9204668/
  2. Olivry T, Mueller RS. Probiotic use in canine atopic dermatitis – systematic review. Vet Dermatol. 2020;31(6):493-509.
    Good for “probiotics may modulate immune markers/skin outcomes” language. Available from: https://pubmed.ncbi.nlm.nih.gov/12791047/
  3. Schäfer L, et al. Essential fatty acids as a steroid-sparing aid in CAD. Vet Dermatol. 2024;35(3):144-152.
    Modern RCT on PUFA with steroid-sparing effect. Use for omega-3 support statement. Available from: https://onlinelibrary.wiley.com/doi/pdf/10.1111/vde.13246?
  4. WSAVA Global Nutrition Guidelines. 2023.
    Use where you advise evaluating labels and declared actives. Available from: https://wsava.org/global-guidelines/global-nutrition-guidelines/
  5. Schmitz S, Suchodolski JS. Understanding the canine intestinal microbiota. J Vet Intern Med. 2016;30(1):37-46.
    Review supporting microbiome-immune linkage. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC5645859/
  6. Chow J, et al. Host–bacterial symbiosis in health and disease. Nature. 2010;468:543-549.
    Foundational review to reinforce the gut-immune interface statement. Available from: https://pubmed.ncbi.nlm.nih.gov/21034976/
  7. Saevik BK, et al. Steroid-sparing effect of essential fatty acids in CAD. Vet Dermatol. 2004;15(6): 369-376.
    Classic RCT showing pruritus/clinical score improvements. Use alongside 3. Available from: https://pubmed.ncbi.nlm.nih.gov/15214949/
  8. Jewell DE, et al. Effect of dietary antioxidants on free radical damage in dogs and cats. Antioxidants. 2024;13(3):350. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC11185959/